The NIH/NCRR Center for Integrative Biomedical Computing
The overall goals of the CIBC are the creation and dissemination of biomedical technology, algorithms, and software for the mathematical modeling, simulation, and visualization of physiological phenomenon applied to problems in clinical and biological research and applications. The Center provides unique computational resources supporting clinical and biological researchers both in fundamental breakthroughs in basic biomedicine and in application of new science and technology to health care. The Center develops software (SCIRun, BioPSE, Seg3D, BioImage, BioTensor, BioFEM and soon BioMesh3D and ImageView3D), distributes it freely to the biomedical community, carries out training, and supports formal and informal collaborators. The Center also carries out technical development and original research in several related areas, including three-dimensional image analysis, scientific visualization, biomedical simulation, bioelectric field problems, problem-solving environments, and software engineering. The CIBC has a strong, ongoing emphasis on software simulation of bioelectric fields, with clinically oriented collaborations in cardiac defibrillation and the diagnosis/treatment of epilepsy. In addition, the CIBC has expanded in recent years to include applications of statistical shape analysis and three-dimensional visualization to mouse genetics and neuroimaging and applications of image and geometry processing to cell biology.
CIBC Wikis:
The ShapeWorks software is an open-source distribution of a new method for constructing compact statistical point-based models of ensembles of similar shapes that does not rely on any specific surface parameterization. The method requires very little preprocessing or parameter tuning, and is applicable to a wide range of shape analysis problems, including nonmanifold surfaces and objects of arbitrary topology. The proposed correspondence point optimization uses an entropy-based minimization that balances the simplicity of the model (compactness) with the accuracy of the surface representations. The ShapeWorks software includes tools for preprocessing data, computing point-based shape models, and visualizing the results. Download ShapeWorks now. |
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Imaging meets Electrophysiology to Help People with Heart Troubles |
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A group of scientists and physicians at the University of Utah is addressing the growing problem of AF through a combination of high tech interventional therapy, multimodal medical imaging, image processing and analysis, and computer science.
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