BE6460 2011
Electrophysiology and Bioelectricity of Tissues
Course Web Page

Important Course Information

This web site is for the Bioengineering course, which is running in the fall semester of 2011. If you are seeing this site after that semester, then treat this as history that may change before we teach the course again, probably in 2013.

• Note class time! Class time and location: Tuesdays and Thuresdays 12:25-1:40 CVRTI library/meeting room on the main floor.
• Course Announcement please forward to anyone who might be interested in the course.
• Course Syllabus (HTML) and in PDF format.
• All Bioengineering students, please sign up for the course as Bioen 6460. Physiology students may sign up as Physiology 6460.
• Course text: there are copies of the text book at the University Bookstore, However, there are many internet sources for the book so please use them to find a good price. You may use either edition and note that the third edition has just come out so prices will drop quickly on the second edition. The course text is also available through the campus network at this link. If you are off campus, try this link
• Course mailing list: to sign up for the class mailing list send an email addressed to:
  sympa@sci.utah.edu
  with this line in the message body.
  

  	subscribe be-6460
        

  You will be sent back a confirmation request just to make sure you really do want to be in the list. After that, you will get all messages sent to the address
  be-6460@sci.utah.edu
  

Course Notes, in PDF formats (Note that some files available in compressed format, with reduced image quality)

• Week #1: Background (RM)
  • Intro
  • Biophysical background.
  • Fields
• Weeks #2: Cellular EP (JB)
  
  • Cellular EP background: resting potential.
• Week #3: Gap Junctions (AM)
  • Background and Review
  • Same notes, 2 slides per page
• Week #4: Microstructure and Conduction (FS)
  
  • Lecture #1
  • Lecture #2
• Week #5: Simulation of Conduction (FS)
  
  • Lecture #1
  • Lecture #2
• Week #6: Propagation and Extracardiac Potentials (DD)
  
  • Propagation of Action Potentials .
  • Electrical Stimulation of Excitable Tissues .
  • Paper on Taser Stimulation .
• Week #7: Extracellular potentials and Measurement (DD)
  
  • Extracellular potentials
  • Paper on sampling
  • Bioelectric Mapping
• Week #8: Arrhythmias (MW)
  
  • Basics of Arrhythmias Pt 1
  • Basics of Arrhythmias Pt 2
• Week #9: Simulation of propagation (FS)
  
  • Simulation of propagation and arrhythmias Pt 1
  • Simulation of propagation and arrhythmias Pt 2
• Week #10: Arrhytymias (MW)
  
  • Arrhythmias Pt 2
• Week #11: Clinical Arrhytymias (RR)
  
  • Clinical Arrhythmias (26 MB)
  • Clinical Arrhythmias (same content) in compressed format (2 MB)
• Weeks #12: Biophsics of ECG (RM)
  
  • Electrocardiography and electroencephalography (9 MB)
  • Compressed version (2.2 MB)
  • Movies:
    
    • Dipole ECG example of ischemia (Slide #21).
    • BSPM example with local scaling (Slide #31) .
    • BSPM example with global scaling (Slide #32).
• Week #13: Clinical ECG (RR)
  
  • Clinical ECG (15 MB)
  • Clinical ECG (same content) in compressed format (1.5 MB)
• Week #14 and #15: Forward-Inverse Problems (RM)
  
  • Forward problems (4.8 MB pdf)
    

Reading Assignments

• ECGSim, a program we will use for homework and in class.

Homework Assignments and Lab Notes

The Assignments

• Assignment #1: Propagation and Stimulation
  • The assignment

  The report from this homework is due by 5:00 pm, Friday, Octomber 7.

• Assignment #2: Arrhytmia Analysisn
  • The assignment
  • The movie

  The report from this homework is due by 5:00 pm, Friday, November 18.

• Assignment #3: Electrocardiography
  
  • Paper on ECGSim,; please read this as background for using the program.
    
  • instructions for the assignment (pdf) .

Useful links and course background material

• Syllabus in HTML, also available as PDF file
• Some notes on effective reading (and writing) of science papers from Dana Brooks (Northeastern University)
• The Science of Scientific Writing, also in pdf format . This is the best article I know for scientific writing. Mandatory reading!
• Additional background information.