Designed especially for neurobiologists, FluoRender is an interactive tool for multi-channel fluorescence microscopy data visualization and analysis.
Deep brain stimulation
BrainStimulator is a set of networks that are used in SCIRun to perform simulations of brain stimulation such as transcranial direct current stimulation (tDCS) and magnetic transcranial stimulation (TMS).
Developing software tools for science has always been a central vision of the SCI Institute.

Events on January 22, 2018

Mark Elliott Presents:

An Automated Imaging Framework Utilizing OCT and Micro-CT to Characterize the 3D In Vivo Vascular Stent Geometry

January 22, 2018 at 12:00pm for 1hr
Evans Conference Room, WEB 3780
Warnock Engineering Building, 3rd floor.

Abstract:

More than 10% of stents will have failure events within a year after intervention, caused mostly be in-stent restenosis or stent thrombosis, and require re-intervention. The non-physiologic biomechanical loads that stents place on coronary arteries have been identified as contributing factors for failure. However, our understanding of the contribution of these factors at the patient-specific level is limited, as computational models lack an understanding of the in vivo deployed-stent geometry. Therefore, the aim of this investigation was to develop a framework to reconstruct this geometry by fusion of intravascular optical coherence tomography (OCT) and micro-computed tomography (µCT) imaging data. Using segmentation techniques on OCT images sparse in vivo stent geometry data is extracted. From a micro-CT scan of a known stent deployment a wireframe model is derived with 15 micrometer voxel resolution. Via diffeomorphic mapping the wireframe is deformed to the sparse OCT-defined geometry, while constraining stent form, resulting in a contiguous 3D reconstructed deployed-stent geometry.

Posted by: Kris Campbell