Designed especially for neurobiologists, FluoRender is an interactive tool for multi-channel fluorescence microscopy data visualization and analysis.
Large scale visualization on the Powerwall.
BrainStimulator is a set of networks that are used in SCIRun to perform simulations of brain stimulation such as transcranial direct current stimulation (tDCS) and magnetic transcranial stimulation (TMS).
Developing software tools for science has always been a central vision of the SCI Institute.

Events on November 20, 2017

Imaging Seminar

Kara Johnson Presents:

Structural Imaging Analysis of Deep Brain Stimulation for Tourette Syndrome

November 20, 2017 at 12:00pm for 1hr
Evans Conference Room, WEB 3780
Warnock Engineering Building, 3rd floor.

Abstract:

TS_DBS_Atlas.pdf

Tourette syndrome (TS) is a debilitating neuropsychiatric disorder characterized by tics, or involuntary movements and vocal outbursts. Some patients experience severe symptoms without relief from conventional therapies. For these patients, deep brain stimulation (DBS) has been explored as an alternative therapy for modulating the neural activity of brain circuits implicated in TS. However, responses to DBS vary greatly across TS patients and we do not have a quantitative understanding of where or how to deliver DBS in order to produce therapeutic response. The goal of this study is to combine structural imaging (MRI, CT) of TS DBS patients to visualize DBS electrode locations in a common brain atlas space to make cross-subject comparisons of electrode locations relative to structural anatomy and their correlation to clinical outcomes. In collaboration with the Tourette Association of America International DBS Registry, we have collected MR and CT imaging for 122 TS DBS patients from 12 sites worldwide. In this seminar, I will outline the image registration methods used to generate an atlas from a heterogeneous imaging dataset and to express DBS electrode locations in this common atlas space.

Posted by: Nathan Galli