Diffusion tensor magnetic resonance imaging (DT-MRI) is relatively new imaging technique which provides new insight into the structure of brain white matter by measuring the local diffusion of water in the brain.  In this project associated with the national alliance for medical image computing (NAMIC) images are combined from a population into a template atlas which reflects the average properties of the population.  White matter bundles are extracted from in the template atlas to serve as a coordinate system for measuring diffusion properties and how they differ between populations.  In a study of neurodevelopment in association with the CONTE center at University of North Carolina - Chapel Hill, an atlas was developed based on subjects at one and two years of age.  Statistical comparison of the diffusion properties between one and two year olds indicates significant changes that may reflect underlying changes in myelination and axon development.  The above image shows differences in the fractional anisotropy (FA), a measure of diffusion tensors which is thought to reflect axon development, from one to two years.  The red regions indicate the largest increase of the FA value.