SCI TV - On Bioimage Informatics and Decoding Genomes
We are now at a time when we can systematically alter animals genetically so that any given protein or its expression can be observed in their cells. Combined with new modalities of light microscopy, this allows us to observe molecular mechanisms within the cell, observe the developmental trajectory of growing organs, and to map the cellular anatomy of organisms and organs such as the brain, the heart, or the stem of a plant. All this increasingly requires computation to either extract information or to quantitatively measure an effect in the vast sea of images produced by such explorations. This is creating the growing sub-field of bioimage informatics.