CIBC:Workshops:Workshop06:summ-kerckhoffs

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Summary for Roy Kerckhoffs

Affiliation

Roy Kerckhoffs, PhD
University of California, San Diego
Department of Bioengineering
Room 243 Powell-Focht Bioengineering Hall
9500 Gilman Drive
La Jolla, Ca 92093-0412
phone: (858) 822-4872
fax: (858) 534-5722

Summary

Here at UCSD in Andrew McCulloch's cardiac mechanics research group, we're developing computational models of cardiac electromechanics, at levels going from cell to whole heart. The latter is coupled to the circulation (system level). That means we're integrating cellular ionic models (for electrophysiology) and myofilament activation models (for mechanics) into our finite element models. These models are used to test hypotheses, provide assistance to setting up experiments, and the final goal will be patient-specific modeling. In the latter, a computational model will be made of a patient, and the effects of all kinds of interventions (pacing, for example) could be investigated to optimize treatment.