Dr. Carston Wolters

The goal of this collaboration is to continue initial progress in linking the software system of the European SimBio project (VGRID, NeuroFEM, and the Inverse Problems Toolbox, IP) to BioPSE. The SimBio programs are powerful software packages for bioelectric brain source localization that will augment and greatly enhance the capabilities of BioPSE. By placing these tools in the context of an integrated problem solving environment, their utility and especially their accessibility will be greatly enhanced. Hence there is strong mutual motivation to bring these two systems into a common framework. It is also important to note that development of the SimBio tools is ongoing so that they will continue to represent the state of the art in advanced source localization algorithms and numerical solvers.

Dr. Carl-Fredrik Westin

This project is a collaboration between Center for Integrative Biomedical Computing and Dr. Carl-Fredrik Westin, Director of the Laboratory of Mathematics in Imaging (LMI) at the Brigham and Women's Hospital. Dr. Westin's research interests are focused on medical applications of image analysis. He is currently working on analysis of Diffusion Tensor MRI data, and automated segmentation and registration of data from MRI, CT, and Ultrasound, using multidimensional signal processing techniques.

NRCAM

The National Resource for Cell Analysis and Modeling (NRCAM) is a Biomedical Technology Resource supported by a grant from the NIH/NCRR. The primary technology they are developing is the Virtual Cell (VC), a software problem solving environment for computational modeling and simulation in cell biology. The NRCAM group has great needs for visualizing multi-variable, dynamic, three-dimensional simulations and plan to use the software components the Center is developing for this purpose. They also will use the Center's tools for three-dimensional image segmentation.

Dr. Ron Kikinis/SPL

This project is a collaboration between Center for Integrative Biomedical Computing and Dr. Ron Kikinis, Director of the Surgical Planning Lab (SPL) at the Brigham and Women's Hospital, Harvard Medical School. Dr. Kikins and members of his lab actively develop, evalute, and refine segmentation and visualization algorithms to increase their practical utility for medical applications. His research interest in this technology collaboration is to incorporate advanced, interactive three-dimensional direct volume rendering techniques into the 3D Slicer (or simply 'Slicer') program. The addition of direct volume rendering into Slicer will complement the current display of discrete polygonal structures, by adding support for the simultaneous visualization of diffuse quantities, such as perfusion and PET data.

Steven Peltier, M.S./NCMIR

The National Center for Microscopy and Imaging Research (NCMIR) is an NCRR/NIH Biomedical Technology Research Center established to develop computer-aided advanced microscopy for acquisition of structural and functional data in the dimensional range of 1nm³ to 100um³. With novel specimen staining methods, imaging instruments and computational capabilities, NCMIR researchers are addressing the next great biological challenges in the post-genomic age by situating proteins and macromolecular complexes in their cellular and tissue environments.